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Pathways of ammonia detoxification to GLN in muscles linked to enhanced use on the BCAA and α-KG (cataplerosis) and proposed outcomes of BCAA and phenylbutyrate in subjects with liver cirrhosis or UCD. Optimistic influence of BCAA on ammonia detoxification to GLN can be blunted by GLN degradation to ammonia in enterocytes and kidneys. Phenylbutyra